New research on cancer treatment “cutting edge”

Nov 10, 2022 | 4:15 PM

PRINCE GEORGE – The BC Cancer Centre for the North has some of the best technology there is for treating cancer, after opening its doors in 2012. But a major part of the work at the centre is research, something oncologist Dr. Rob Olson is heavily invested in. He is part of an international study on a different form of cancer treatment: high-precision therapy that delivers substantially higher doses of radiation to a tumour.

“It’s treating the lung lesions because the breast cancer has already been dealt with many years ago,” explains Dr. Olson. “So yeah, it’s treating the spread, and this specific trial, it’s called Saber Five. It’s a phase two trial, quite large, almost 400 patients. And the primary outcome was looking at side effects. And the reason we’re looking at side effects is that the study that came before it, which we were part of, actually had double the survival. So people live longer if they got saber great news but three times the side effects and so mild side effects happened 30% of the time serious side effects happened 15% of the time.”

Stereotactic ablative radiotherapy, or SABR, is cutting-edge therapy for radiation therapy. And Dr. Olson’s work is very specific involving a number of different techniques.

“So I would outline the tumors but also carve the dose away from the normal struct structure such as the esophagus. If you’re treating a lung cancer. And so that was one thing that made it better. The other thing is that when you’re planning radiation, you’re always prioritizing, giving the high dose to the tumor while sparing the normal tissue that’s close by.”

Dr. Olson’s work has been published in the Journal of the American Medical Association and will become the gold standard of radiation therapy.

“So for sure, this paper is like the landmark study from looking at side effects, it’s the most comprehensive look at side effects from Saber. And so internationally this is well-regarded it’s you know the topic of lots of interest and so it is the standard and what people are going to do is they’re going to look at the techniques we use for the radiation.”

The researchers on this work are partway through the third phase of research, of which the results will not be fully understood for years to come.