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By James Peters

Toxic Drugs

Northern Health issues alert for extremely toxic drug that responds to naloxone

Mar 29, 2025 | 11:20 AM

• correction: The original version of this story stated that “Isotonitazene or ‘Nitazene” does not respond to naloxone. That statement was incorrect. It does respond to naloxone.

PRINCE GEORGE — Northern Health is alerting those who use drugs about a substance being sold in the region that is “more toxic than fentanyl.”

The substance comes in the form of a white pill sold as oxycocet. However, the pill has tested positive for another substance, isotonitazene.

“Isotonitazene or ‘Nitazene’ is a synthetic opioid that is equal or more toxic than fentanyl and is not detected on fentanyl test strips,” said Northern Health in a news release issued Thursday (March 27).

Those who use drugs are advised not to use alone.

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